Abstract

Asthma is a common chronic illness that imposes a heavy burden on all aspects of the patient's life, including personal and health care cost expenditures. To analyze the direct cost associated to uncontrolled asthma patients, a cross-sectional study was conducted to determine costs related to patients with uncontrolled and controlled asthma. Uncontrolled patient was defined by daytime symptoms more than twice a week or nocturnal symptoms during two consecutive nights or any limitations of activities, or need for relief rescue medication more than twice a week, and an ACQ score less than 2 points. A questionnaire about direct cost stratification in health services, including emergency room visits, hospitalization, ambulatory visits, and asthma medications prescribed, was applied. Ninety asthma patients were enrolled (45 uncontrolled/45 controlled). Uncontrolled asthmatics accounted for higher health care expenditures than controlled patients, US$125.45 and US$15.58, respectively [emergency room visits (US$39.15 vs US$2.70) and hospitalization (US$86.30 vs US$12.88)], per patient over 6 months. The costs with medications in the last month for patients with mild, moderate and severe asthma were US$1.60, 9.60, and 25.00 in the uncontrolled patients, respectively, and US$6.50, 19.00 and 49.00 in the controlled patients. In view of the small proportion of uncontrolled subjects receiving regular maintenance medication (22.2%) and their lack of resources, providing free medication for uncontrolled patients might be a cost-effective strategy for the public health system.

Highlights

  • Asthma is one of the most common chronic diseases and affects a million people in the world [1]

  • To analyze the direct cost associated to uncontrolled asthma patients, a cross-sectional study was conducted to determine costs related to patients with uncontrolled and controlled asthma

  • Direct costs over a 6-month study period were related to asthma control, maintenance medication use, and health care expenditures

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Summary

Introduction

Asthma is one of the most common chronic diseases and affects a million people in the world [1]. According to data of population-based surveys there is a gap between asthma management as stipulated by GINA and the achievement of asthma control around the world [2,3,4,5,6]. These studies have shown high levels of both emergency room visits and hospitalization despite the availability of effective therapies to achieve asthma control. One of the most relevant socioeconomic impacts of this disease is the heavy burden of direct expenditures related to health care costs due to uncontrolled asthma, causing unscheduled clinical visits, emergency room attendance and hospitalizations. Improving asthma control reduces hospitalization costs, in contrast to an increase of expenditures with maintenance medications [7]

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