Abstract
This study presents electron microscopical evidence for direct synaptic contact between primary trigeminal axonal (PR) endings and trigeminocerebellar projection neurons (TCPNs), in the border zone (BZ) of rat trigeminal nucleus oralis. The combined techniques of anterograde degeneration following trigeminal sensory root rhizotomy and retrograde transport of horseradish peroxidase subsequent to injections into the orofacial tactile portions of crural I and II of the cerebellar hemispheres were utilized. Degenerating PR endings lie centrally in glomeruli where they form axodendritic synapses on higher order dendrites of identified BZ TCPNs. It is at these synapses that the PR endings are probably transferring tactile input to BZ TCPNs for direct relay to the cerebellar cortex. Transmitter release at the axodendritic synapses may be modified within the glomeruli by axoaxonic synapses between terminals containing flattened synaptic vesicles and the PR ending.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
