Abstract
Background Myocardial CT perfusion is a relatively new technique which enables the assessment of perfusion deficits through first pass imaging in combination with pharmacological stress. Comparison of CT and MR perfusion has been limited and in-vivo assessment is affected by physiological variability, acquisition timing during firstpass contrast perfusion and parameter selection. We utilized a myocardial perfusion phantom to precisely compare high resolution k-t SENSE MR perfusion with single phase CT perfusion under identical imaging conditions.
Highlights
Myocardial CT perfusion is a relatively new technique which enables the assessment of perfusion deficits through first pass imaging in combination with pharmacological stress
CT perfusion studies were performed with a Philips iCT (256 slice) CT, with isotropic resolution of 0.6mm3 and contrast dosing according to clinical protocols
Contrast by CT perfusion is highly dependent on photon energy and to a lesser extent on timing of CT acquisition within the myocardial perfusion upslope
Summary
Myocardial CT perfusion is a relatively new technique which enables the assessment of perfusion deficits through first pass imaging in combination with pharmacological stress. Comparison of CT and MR perfusion has been limited and in-vivo assessment is affected by physiological variability, acquisition timing during firstpass contrast perfusion and parameter selection. We utilized a myocardial perfusion phantom to precisely compare high resolution k-t SENSE MR perfusion with single phase CT perfusion under identical imaging conditions
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