Abstract
During 2015–2018, seven schools in rural Vietnam experienced diphtheria outbreaks. Multilocus sequence types were the same within schools but differed between schools. Low vaccine coverage and crowded dormitories might have contributed to the outbreaks. Authorities should consider administering routine vaccinations and booster doses for students entering the school system.
Highlights
During 2015–2018, seven schools in rural Vietnam experienced diphtheria outbreaks
It has been predicted that age of diphtheria case-patients could increase after introduction of diphtheria–tetanus–pertussis vaccine (DTP) because a high proportion of older persons will be susceptible to the disease due to reduced circulation of bacteria, especially when no booster dose is provided [8]
The 4 multilocus sequence typing (MLST) types identified in this study (ST67, ST209, ST243, and ST244) were identified in Thailand, Cambodia, the Philippines, and Binh Phuoc Province in Vietnam in the 2010s [4,9,10]
Summary
During 2015–2018, seven schools in rural Vietnam experienced diphtheria outbreaks. Multilocus sequence types were the same within schools but differed between schools. Diphtheria cases had become sporadic by 2010, beginning in 2013, outbreaks occurred in the western and central highland areas of Vietnam, which prompted our study [4]. The Study During June 2015–April 2018, the Pasteur Institute in Nha Trang, Vietnam, and the provincial health authority investigated 46 cases involving patients with
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