Abstract

1. 1. The compounds 2,3-diphosphoglycerate (DPG), phytic acid (PA) and adenosine triphos- phate (ATP) were tested as gorging stimulants for Rhodnius prolixus. All three are potent phagostimu- lants, with ED 50 values less than 10 μM; in contrast, only ATP stimulates the black fly Simulium venustum, with an ED 50 of 13 μM. 2. 2. Equimolar mixtures of DPG and ATP showed pronounced synergism, causing 75% of test R. prolixus to gorge at a dose of 0.3 μM. 3. 3. The response to DPG and PA supports the hypothesis that R. prolixus detects blood during biting by tasting signal chemicals released from red blood cells.

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