Dimensions of activities of daily living in subjective cognitive complaint elderly. The GERO Cohort

Abstract

AbstractBackgroundSubjective cognitive complaint (SCC) is a risk factor of functional impairment in activities of daily living (ADL). ADL are divided from basic (BADL), instrumental (IADL), and advanced activities of daily living (a‐ADL), according to their cognitive complexity. These three dimensions of ADL have been scarcely explored in SCC The objective of this study was to analyze these three dimensions of ADL and their association with global cognition and sociodemographic factors in SCC.Method291 participants from the GERO prospective cohort study of community‐dwelling elderly with SCC, aged 70 or older, living in Santiago ‐ Chile were analyzed. ADL were evaluated with the Technology Activities of Daily Living Questionnaire (T‐ADLQ), an informant‐rated questionnaire measuring BADL, IADL and aADL (T‐ADLQ total score and dimension score range 0‐100, higher values meaning worse performance), global cognition with the Mini‐mental state (MMSE) and sociodemographic factors measured with age, gender, marital status, education, household‐income, working status. A multivariate logistic regression model was performed considering MMSE and sociodemographic factors as explanatory variables and the different dimensions of ADL as dependent variables. Results were evaluated with coefficient of regression and 95% confidence intervals.ResultPerformances in T‐ADLQ total score ranged from 0 to 56; in BADL from 0 to 40; in IADL from 0 to 67 and a‐ADL from 0 to 100. T‐ADLQ total score was independently associated with MMSE (Coef: ‐0.24), age (Coef: 0.40) and marital status (Coef: 3.44), BADL with age (Coef: 0.14), IADL with age (Coef: 0.45) and marital status (Coef: 3.59), a‐ADL with marital status (Coef: 7.25). Results are presented in Table 1.ConclusionImpairment in ADL and their associated factors in SCC differ according to their complexity, being the aADL the most affected. Studying dimensions of ADL could contribute to better understanding functionality in SCC.Slachevsky, A., …, Thumala, D. (2020). GERO Cohort Protocol, Chile, 2017‐2022: Community‐based Cohort of Functional Decline in Subjective Cognitive Complaint elderly. BMC geriatrics, 20(1), 505.Slachevsky, A., … Hornberger, M. (2019). Mapping the neuroanatomy of functional decline in Alzheimer’s disease from basic to advanced activities of daily living. Journal of neurology, 266(6), 1310‐1322Funding: ANID/FONDAP/15150012; ANID /FONDECYT/ 1231839 and ANID/PIA/ANILLOS ACT210096.