Dimensional Assessment of the Heart in Hypertrophic Cardiomyopathy Patients in Tertiary Care Hospitals

Rayhan Shahrear,Mohiuddin Masum

doi:10.7575/aiac.abcmed.v.9n.2p.11

Abstract

Hypertrophic cardiomyopathy (HCM) is one of the most prevalent disorders responsible for sudden cardiac death. Presentation of the symptoms varies due to the degree of thickening, and functional ability of the cardiomyocytes. The aims of the current study were to assess the clinical features, and cardiac morphology. This was a descriptive study with some analytical components. Thirty-four adult HCM patients were included within a duration of four months by patient selection checklist. After informed written consent, relevant information was noted and analyzed. Frequency distribution of phenotypes were, 56% asymmetric septal hypertrophy, 29% concentric hypertrophy, and 15% apical hypertrophy. Breathlessness and chest discomfort were present in 56% and 62% patients respectively, and higher in asymmetric septal HCM. Palpitation was very frequent in concentric HCM (90%). ECG revealed left ventricular hypertrophy in 85% of patients, and 79% of them had ST change. The interventricular septal thickness was narrower in apical type (14.80mm). The posterior wall thickness was higher in concentric HCM (19.20mm). The left atrial size was smaller in Concentric type(34.60mm).

Highlights

Hypertrophic cardiomyopathy (HCM) is one of the most common genetically predisposed cardiomyopathies [1, 2]
The phenotypic classification is widely used by clinicians which is based on the distribution of the hypertrophied cardiac muscles is like the following: (a) asymmetrical septal HCM is the commonest to be seen and it is diagnosed when the interventricular septum is predominantly involved, (b) the common pattern is concentric hypertrophy, where the cardiac wall is diffusely hypertrophied, and (c) the apical type occurs when the apical cardiac muscle is involved [11,12,13,14,15,16]
Among the thirty-four HCM patients, 56% of patients had asymmetric septal hypertrophy (ASH), 29% had concentric hypertrophy, and 15% had the apical type of HCM

Summary

Introduction

Hypertrophic cardiomyopathy (HCM) is one of the most common genetically predisposed cardiomyopathies [1, 2]. The phenotypic classification is widely used by clinicians which is based on the distribution of the hypertrophied cardiac muscles is like the following: (a) asymmetrical septal HCM is the commonest to be seen and it is diagnosed when the interventricular septum is predominantly involved, (b) the common pattern is concentric hypertrophy, where the cardiac wall is diffusely hypertrophied, and (c) the apical type occurs when the apical cardiac muscle is involved [11,12,13,14,15,16]. The clinical profile of HCM received more focus from the researchers, but data relating with morphological change is scarce

Objectives

Methods

Results

Conclusion