Abstract

Serotonin syndrome is an increasingly common clinical diagnosis due to increased utilization of SSRI’s, SNRI’s and other antidepressants. Despite its increasing incidence, the disease is often missed by clinicians, given the disease’s varied and diverse clinical presentations. Serotonin syndrome has a set of diagnostic criteria known as the Hunter Criteria to establish a diagnosis. The Hunter Criteria include exposure to a serotonogenic agent in the last 5 weeks and either spontaneous clonus, inducible clonus with agitation or diaphoresis, ocular clonus with agitation or diaphoresis, tremor and hyperreflexia, or hypertonia, temperature greater than 38 C and ocular or inducible clonus.

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