Abstract

The sidechain of the germacranolide stizolicin was oxidized by CrO 3 in Py to form a lactone. The structure of the product was established as 4,5α-epoxy-7α,5,6,8β(H)-germacr-1(10),11(13)-dien-8 α(3′-oxo-2′,5′dihydrofuran-3′-carboxylyl)-12,6-olide using spectral data.

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