Abstract

New disaccharide mimics connecting 4-amino-4-deoxyerythrofuranose at C(1) to position C(3) of galactose through a CH(OH) link have been prepared as racemates and tested toward 25 commercially available glycohydrolases. One of them ( 2) is a moderate but specific (43% of inhibition at 1mM) inhibitor of jack bean α-mannosidase.

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