Abstract
Because the peritoneum is a living membrane, its blood supply, unlike that of hemodialyzer membranes, responds to physiological and pharmacological influences. Such changes in peritoneal hemodynamics affect transport parameters. Although the influence of vasodilators on peritoneal transport parameters is more complex than a simple increase in solute and fluid delivery, these effects are generally correlated with blood flow rates rather than with splanchnic blood volume. Most drugs change splanchnic blood flow rates and volume in parallel and do not distinguish these two parameters.
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