(Digital Presentation) Novel Porous Functionalized Mwcnts-TiO2/g-C3N4 heterostructure Modified Screen Printed Electrode for a Rapid Enzyme-Free Detection of Uric Acid in Human Urine

Abstract

Porous heterostructures gained wide appreciation for their escalated sensing performance in electrochemical society. In the present work, we report the porous functionalized MWCNTS-TiO2/g-C3N4 (f-MWTGCN) heterostructure modified screen-printed electrode for the detection of uric acid in human urea samples. The f-MWTGCN are synthesized via a two-step combination process by hydrothermal-assisted ultrasonication construction. The fabricated powders are subjected to X-Ray diffraction to identify the size, structure, dislocation densities, and micro strain. The morphological studies are performed by the FESEM and HRTEM analysis to identify the confinement of heterostructures. The required chemical analysis was obtained from the FTIR and Raman studies and substantiated the qualitative and quantitative vibrational modes. The obtained highly porous ultrafine powders are drop cast on the screen-printed electrode to modify the working electrode to achieve super ultrafast sensing. Functionalization of MWCNTs facilitated the carbon to attain hydroxyl, carboxyl, and carbonyl functional groups which assisted in the rapid detection of uric acid. The reproducibility and stability of the electrode were evaluated by the fifteen repeated cyclic voltammetry responses to 0.1M uric acid. The developed sensors showcased a detection of Limit (DoL) of 1.17 µM and sensitivity of 98.1 nA µM-1 with a range of two to three seconds. The utilization of the developed heterostructure for modifying screen-printed electrodes and sensing uric acid is a unique and novel approach. Thus, the fabricated highly stable sensor may be utilized as the uric acid sensor in biomedical applications. Keywords: Porous, Heterostructures, Functionalized MWCNTS, Reproducibility, and Hydrothermal.