Digital Neuropsychological Assessment of Cognitive Functions in Patients with Epilepsy.

Abstract

Cognitive impairment often occurs secondary to epilepsy. This study aims to evaluate the cognitive functions of patients with idiopathic generalized epilepsy (IGE) by using the digital neuropsychological assessment. Seventy-nine patients diagnosed with IGE in the last 10 years in our clinic, who completed at least eight years of education were recruited. Participants who met the criteria were 36 individuals with IGE syndrome as well as 36 healthy individuals between the ages of 18-48. All volunteer participants were administered the standardized mini mental test (SMMT) and the Beck depression scale (BDS). For the neurocognitive assessment, participants completed five tasks in TestMyBrain digital neuropsychology test battery (TMB) which are TMB digit span, TMB choice reaction time test, TMB visual paired associates test, TMB matrix reasoning, and TMB digit symbol matching assessing a variety of cognitive domains. IGE patients showed lower cognitive performance in attention, short-term memory, working memory, visual memory, episodic memory, cognitive processing speed, response selection/inhibition, fluid cognitive ability, and perceptual reasoning domains. The results show that IGE patients have cognitive dysfunction in many cognitive domains. IGE patients performed significantly worse outcomes in some tests of the TMB. In this study, it is aimed to emphasize the necessity of evaluating the cognitive aspects of epilepsy patients, which will be of great importance in their functionality, in addition to providing symptomatic treatment in order to control their seizures.