Abstract
AbstractAnxiety and depressionAntidepressant weight gain Anti ‐ depressants are another class of drugs associated with weight gain but a new meta‐analysis of 116 studies identifies some that carry the greatest risk (J Clin Psychiatry 2010;71:1259‐72). Amitriptyline, mirtazapine and paroxetine were associated with the highest risk of weight gain whereas bupropion and acute use of fluoxetine were associated with weight loss. Evidence for other agents was inconclusive.Anxiolytic abuse Drugs for anxiety have abuse potential and, say US investigators, there is a link between prescribing and abuse (Am J Psychiatry 2010;167:1247‐53). Using national survey data from 34 653 adults, they found that the prescription of anxiety medication was associated with a 90 per cent increased risk of non‐medical use in the previous year and a 2.6‐fold increase in the risk of lifetime abuse or dependence. Of those given a prescription, non‐medical use was associated with a history of drug use, crime and young, white men. Copyright © 2010 Wiley Interface Ltd
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