Abstract

[129932-29-2] C13H11F2OP (MW 252.20) InChI = 1S/C13H11F2OP/c14-13(15)17(16,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10,13H InChIKey = BWWJPRJTQKEZQL-UHFFFAOYSA-N (utilized for the synthesis of 1,1-difluoro olefins (CF2) from carbonyl compounds) Physical Data: white crystalline solid, mp 93–94 °C.1 Solubility: soluble in THF, CH2Cl2, and ethyl acetate. Preparative Methods: prepared by the lithation of commercially available diphenylphosphine oxide [Ph2P(O)H] with n-BuLi in THF at a low temperature followed by alkylation with chlorodifluoromethane (CHClF2).1 column chromatography (flash silica, 2:1 toluene– ethyl acetate), recrystallization.

Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call