Abstract
A facile difluoroalkylation and 1,2-aryl migration reaction commencing from allylic alcohols and simple BrCF2COOEt was developed. This metal-free method offers chemists green and efficient access to important difluoro 1,5-dicarbonyl compounds in moderate to good yields with good functional group tolerance. Sodium hydrosulfite was used as a low-toxic, cheap, environmentally friendly, and efficient radical initiator. The feasibility of performing the transformation on a large scale potentially allows the further application of the present method in other fields.
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