Diffusion-weighted imaging in the evaluation of perianal fistula and abscess

Laila Adel Mohsen,Nasr Mohamed Osman

doi:10.1186/s43055-020-00193-3

Laila Adel Mohsen, Nasr Mohamed Osman

Open Access

https://doi.org/10.1186/s43055-020-00193-3

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Abstract

BackgroundPerianal fistulas are a common inflammatory condition of the anal canal and perianal tissue. The introduction of MRI in the evaluation of suspected perianal inflammation has greatly improved the surgical outcome of these patients as it allowed the direct visualization of anal sphincters, levator ani muscle, and the extent of the disease in relation to these vital structures. Diffusion-weighted imaging (DWI) has been under extensive research to evaluate whether it adds any value in the setting of perianal inflammation.The aim of our study was to evaluate the visibility of perianal inflammation on DWI and evaluate the diffusion characteristics of perianal fistulas and abscesses and how accurately can DWI classify perianal disease.ResultsMean age of patients was 37 ± 8.9 years old. The study included 30 fistulas and 15 abscesses. Seven patients had more than 1 fistula or fistula and abscess. Perianal abscesses were well visualized equally on DWI and T2W images and correctly classified by DWI, when compared to post-contrast images. Perianal fistulas without abscesses, on the other hand, had variable visibility scores. Although the visibility of these fistulas on DWI was generally less than T2W and combined DWI and T2W, yet this did not reach a significant level and it was not significantly different between positive and negative inflammatory groups. Combined DWI and T2W evaluation had the highest performance and accurately classified 97.8 % of perianal fistulas and abscesses, and only 1 case was misclassified (2.3%).ConclusionDWI had a good performance in the evaluation of perianal inflammatory disease. However, combined DWI and T2W evaluation had better performance which was not significantly different from combined T2W and post-contrast images.

Highlights

Perianal fistulas are a common inflammatory condition of the anal canal and perianal tissue
In our study, we concluded that Diffusion-weighted imaging (DWI) alone was not superior to T2W regarding the visibility of perianal fistulas and abscesses
The best performance was for combined DWI and T2W evaluation, it was not significantly higher than either sequence alone

Summary

Introduction

Perianal fistulas are a common inflammatory condition of the anal canal and perianal tissue. Perianal fistulas represent a common inflammatory condition of the anal canal and perianal tissues. Most of these fistulas occur due to idiopathic inflammation of the cryptogenic glands in the anal mucosa. Diffusion-weighted imaging (DWI) has been studied by several researchers to evaluate whether it adds any value to other MRI sequences in the evaluation of perianal inflammation. Others suggested that restricted diffusion indicated activity of the fistula, and some even suggested that it represents a good alternative for post-contrast imaging in case gadolinium cannot be used [2, 3] These studies are still few, and the applicability of DWI in the imaging of perianal fistulas is still questionable

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