Abstract
The osmotic permeability coefficient ( L p ) for human red cells has been reported to depend on the osmolality of the suspending solution. These results are also consistent with the view that the value of L p depends on flow rectification. In this report an NMR method is used to measure the dependence of water exchange times at constant cell volume on osmolality. Our results indicate that the diffusion water permeability is constant over a large range of osmolality (300–1000 mosM) produced by the permeable solutes urea, methanol, ethanol, and glycerol. The results support the view that the apparent dependence of L p on osmolality is due to flow rectification.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
More From: Biochimica et Biophysica Acta (BBA) - Biomembranes
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.