Diffusion tensor imaging in evaluation of intradural spinal tumors – A case series

Abstract

Diffusion tensor imaging (DTI) is an advanced magnetic resonance imaging (MRI) technique which utilizes diffusion measurements in multiple directions to provide information regarding tissue structure by parameters such as fractional anisotropy (FA) and apparent diffusion coefficient along with generation of fiber tractography maps. We investigated DTI using single shot echo planar imaging in 20 diffusion directions on 3T MRI in nine patients diagnosed with intradural spinal tumors and found significant reduWction in FA value within the lesion compared to FA value at normal cord. Tractography maps generated by DTI were useful in differentiating intramedullary from extramedullary location of tumor. Tractography also provided useful information regarding tract infiltration or displacement in cases of intramedullary neoplasms. Thus, DTI proved helpful in classification, characterization, and treatment planning of intradural spinal tumors.