Abstract
Chronically shunted patients with functioning shunts are often characterized as having slit or smaller than normal ventricles and chronic headaches. In this study, we used Diffusion Tensor Imaging (DTI) to quantitatively analyze the directionality of water diffusion in the internal capsule (IC) and the corpus callosum (CC) in these patients which have been shown to be affected in untreated hydrocephalus patients [1].
Highlights
Shunted patients with functioning shunts are often characterized as having slit or smaller than normal ventricles and chronic headaches
White matter ROIs were manually drawn on high-resolution T1-weighted images with the aid of fractional anisotropy (FA) maps to locate the internal capsule (IC), genu and splenium of the corpus callosum (CC) and were verified by a neuroradiologist
A statistically significant decrease in FA was found in the patient group compared to the controls in the right posterior (FA=0.61 vs 0.65, p=0.0045), left posterior (FA=0.61 vs 0.66, p
Summary
Shunted patients with functioning shunts are often characterized as having slit or smaller than normal ventricles and chronic headaches. We used Diffusion Tensor Imaging (DTI) to quantitatively analyze the directionality of water diffusion in the internal capsule (IC) and the corpus callosum (CC) in these patients which have been shown to be affected in untreated hydrocephalus patients [1]
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