Diffuse pulmonary interstitial emphysema in a late preterm neonate without mechanical ventilation

Abstract

Abstract Pulmonary interstitial emphysema (PIE) is most commonly seen in the setting of preterm, low birth weight neonates with lung disease. It exists on a spectrum with pneumomediastinum and pneumothorax and is often a transient phenomenon. This condition has been rarely reported in neonates while only on nasal continuous positive airway pressure (CPAP) without mechanical ventilation, but only as a localized presentation. We present a case of a late preterm neonate with diffuse PIE complicated by bilateral pneumothoraces, requiring chest tubes, with congenital thyroid aplasia as well.