Abstract
Background It is unclear if children after heart transplantation (HTX) are at risk for developing increased myocardial fibrosis. Diffuse myocardial fibrosis can be estimated by myocardial longitudinal relaxation (T1) times. Methods Twenty cardiovascular magnetic resonance (CMR) studies in 17 patients after HTX (mean age 13.2 years, range 1.2 17.4 years, 9 female) were analysed retrospectively and compared to CMR studies in nine healthy controls
Highlights
From 17th Annual SCMR Scientific Sessions New Orleans, LA, USA. 16-19 January 2014. It is unclear if children after heart transplantation (HTX) are at risk for developing increased myocardial fibrosis
T1 measurements were performed at a single mid-ventricular short axis slice orientation before and > 10 minutes after the application of 0.2 mmol/kg gadopentetate dimeglumine (Gd) in the interventricular septum (IVS), LV lateral wall and the complete LV myocardium (Image)
Pre-contrast T1 times before the application of Gd were significantly higher in HTX patients compared to controls (LV lateral wall 977 ± 40 msec. versus 923 ± 12 msec., p < 0.001; IVS 1008 ± 32 msec. versus 974 ± 21 msec., p < 0.005; complete LV myocardium 992 ± 34 msec. versus 951 ± 16 msec., p < 0.005), whereas the reduced post-contrast T1 times in the HTX patients showed a trend towards being shorter than in controls but failed to reach statistical significance
Summary
It is unclear if children after heart transplantation (HTX) are at risk for developing increased myocardial fibrosis. Diffuse myocardial fibrosis in children after heart transplantation Background It is unclear if children after heart transplantation (HTX) are at risk for developing increased myocardial fibrosis. Diffuse myocardial fibrosis can be estimated by myocardial longitudinal relaxation (T1) times.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
