Abstract
Dysembryoplastic neuroepithelial tumor (DNT) considered as a benign cortical glioneuronal neoplasm of children or young adults, typically present with drug-resistant focal epilepsy. DNTs are usually located in the temporal lobe but can found in any part of the supratentorial brain cortex. Multifocal DNTs have rarely reported. Here we present an eight years old boy with two years follow up, having a somewhat stable diffuse multinodular DNT of the most significant spatial extent that may have reported, involving cortical and subcortical left temporo-occipital lobe, bilateral basal ganglia and thalamus, presenting with headache, short stature, and behavioral disorder.
Highlights
Dysembryoplastic neuroepithelial tumor (DNT) was first introduced as a new tumor entity by Professor Chaterine Daumas-Duport in 1988.1 DNT regarded as a WHO grade I tumor and is the second most common diagnosis of the specimens receiving from intractable epileptic surgeries.[2]
WHO classification of tumors of the central nervous system in 2016 defined DNT as “a benign Glioneuronal tumor usually located in the temporal lobe of children or young adults with drugresistant epilepsy; typically, with a cortical location and multinodular structure.”
DNTs have reported in any part of the supratentorial cortex, and only a few multifocal DNTs have reported in the English literature
Summary
Hassan Reza Mohammadi[1], Ehsan Moradi[1] ID , Elham Rahimian[2], Pascal Varlet[3] ID , Yalda Nilipour[4] ID
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