Abstract
Diffuse large B-cell lymphoma (DLBCL) is an aggressive type of non-Hodgkin lymphoma. A 38-year-old male patient was referred presenting an exuberant, asymptomatic, and reddish swelling in the mental region of the face, with progressive growth for the last 3 months. Intraoral examination revealed an ulcerated nodule in the lower anterior vestibule, which produced slight resorption of the buccal bone cortical of the anterior mandible and displacement of anterior teeth. Intraoral incisional biopsy was performed, and microscopic examination revealed proliferation of atypical large lymphoid cells, which were immunopositive for CD20, PAX-5, BCL-6, MUM-1, CD30, and Ki-67 (90%) and negative for CD3 and CD10. The final diagnosis was DLBCL. The patient is under follow-up after the first cycle of chemotherapy, and the tumor has decreased totally in size. DLBCL may appear as a reddish swelling of the face with extension to the oral cavity. Diffuse large B-cell lymphoma (DLBCL) is an aggressive type of non-Hodgkin lymphoma. A 38-year-old male patient was referred presenting an exuberant, asymptomatic, and reddish swelling in the mental region of the face, with progressive growth for the last 3 months. Intraoral examination revealed an ulcerated nodule in the lower anterior vestibule, which produced slight resorption of the buccal bone cortical of the anterior mandible and displacement of anterior teeth. Intraoral incisional biopsy was performed, and microscopic examination revealed proliferation of atypical large lymphoid cells, which were immunopositive for CD20, PAX-5, BCL-6, MUM-1, CD30, and Ki-67 (90%) and negative for CD3 and CD10. The final diagnosis was DLBCL. The patient is under follow-up after the first cycle of chemotherapy, and the tumor has decreased totally in size. DLBCL may appear as a reddish swelling of the face with extension to the oral cavity.
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