Diffuse and Aggressive Cutaneous Granulomatosis Revealing a Cytotoxic Cell Systemic Lymphoma

Abstract

Sir, Systemic lymphomas may give rise to a variety of nonspecific skin manifestations, such as pigmentation, urticaria, erythroderma, ichthyosis, erythema multiforme, erythema nodosa (1) and, rarely, cutaneous granulomas. The development of non-infectious granulomas in involved and non-involved organs, such as spleen, liver, bone marrow or lymph nodes, is a classical occurrence in systemic lymphomas, even though skin involvement is less frequently reported (2–4). We report here a patient with diffuse sarcoidosis-like granulomatous skin lesions associated with and revealing a Hodgkin’s-like T-cell systemic lymphoma.