Abstract
Abstract An unknown spot, observed on two-dimensional paper chromatograms of extracts of human urine, was identified as N-acetyl-p-aminophenol (APAP), a drug metabolite. This finding suggests that APAP is clearly separable from other endogenous phenolic compounds in urine by a two-dimensional paper chromatographic method. This simple technique is feasible for the specific routine analysis of APAP in urine.
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