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Abstract
To differentiate between Il'in-Bykovskii virus (IBV) and Mason-Pfizer monkey virus (MPMV) the method of neutralization of the viruses by antisera against virus envelope antigens was used. The viruses were cultured on the same human embryonic cells. The results of virus neutralization were determined by the presence or absence of gs antigen in the affected cells. Antiserum against IBV envelope antigens neutralized IBV but not MPMV. Antiserum against MPMV did not neutralize IBV. It is concluded that IBV and MPMV differ in their virus envelope antigens and must be regarded as different viruses.
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