Abstract
In the rat fundic mucosa, increase in the peptic activity of pepsinogen, changes in the molecular species of pepsinogen separated by electrophoresis and changes in the morphology of the chief cells indicated that maturation of the chief cells began around 15 days after birth, and was complete 25–30 days after birth. In the rat pyloric mucosa, no changes in the peptic activity or molecular species of pepsinogen or in the morphology of pyloric gland cells occurred after birth. These results suggest that maturation of pyloric gland cells is complete before birth.
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