Abstract
Background The objective of this study is to differentiate PSP from Parkinson's disease through magnetic resonance imaging. Methods We included 14 consecutive patients with PD (9) or PSP (5). These measures included the third ventricle, midbrain diameter, quadrigeminal plate, brainstem volumetry, and interpeduncular angle. Results Patients with PSP presented enlargement of third ventricle (100% vs. 33%), lower midbrain diameter (mean 13.2±1.7 mm vs. 16.5±1.7 mm) and thinning of the quadrigeminal plate (mean 2.7±0.3 mm vs. 3.6±0.3 mm) in comparison with PD. Conclusions Characteristic findings on MRI may help to differentiate PD from PSP.
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