Abstract
Background Qualitative assessment of myocardial T2-weighted and late enhancement (LGE) images has been demonstrated to differentiate acute from chronic myocardial infarction (AMI, CMI). Parametric mapping could help to overcome challenges in image quality and could contribute to making contrast media application obsolete. The aim of this pilot study was to analyze, whether T2and T1maps are useful to discriminate AMI from CMI.
Highlights
Qualitative assessment of myocardial T2-weighted and late enhancement (LGE) images has been demonstrated to differentiate acute from chronic myocardial infarction (AMI, CMI)
Five independent experienced readers, blinded to the patients’ clinical state, qualitatively assessed the presence of an infarct-like myocardial lesion in three short axes acquired with several techniques: i) T2-weighted STIR, ii) T2-map based on 3 single-shot SSFP images with different T2-preparation times, iii) native T1-map based on modified LookLocker inversion recovery using 11 single-shot SSFP images, iv) T1-map 10 minutes after 0.2 mmol/kg body weight gadobutrol, and v) PSIR LGE
In the remaining image sets, STIR showed an infarct-like lesion in 82.9% of AMI and 27.8% of CMI, LGE in 95%/100%, T2-map in 69.2%/35.0%, native T1-map in 86.8%/57.5%, and postcontrast T1-map in 95.0%/91.9%
Summary
Differentiation of acute and chronic myocardial infarction using T2-weighted imaging, late enhancement and T1 and T2 mapping - a pilot study at 3T. Florian von Knobelsdorff1,2*, Marcel Prothmann, Matthias A Dieringer, Ralf Wassmuth, André Rudolph, Wolfgang Utz, Julius Traber, Andreas Greiser, Thoralf Niendorf, Jeanette Schulz-Menger. From 17th Annual SCMR Scientific Sessions New Orleans, LA, USA. From 17th Annual SCMR Scientific Sessions New Orleans, LA, USA. 16-19 January 2014
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