Abstract
The differentiation between terminal zones and pathological signal intensity changes on MRI of children and young adults is of diagnostic importance. We assessed the diagnostic value of several morphological features on MRI to differentiate between terminal zones and hypoxic–ischemic white matter injury. We selected all brain MRI examinations performed in subjects up to 20 years of age showing increased signal intensity on T2-weighted images in the peritrigonal areas. Seventy-five individuals were assigned to a patient group (n=28) if there was evidence of hypoxia–ischemia during the perinatal period or a control group (n=47).
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