Abstract
Differentiation between benign and malignant thyroid nodules by diffusion weighted image and apparent diffusion coefficient
Highlights
There is a great increase in the incidence of thyroid cancer
Aim of the Work The purpose of the study is to evaluate the diagnostic accuracy of diffusion weighted imaging and apparent diffusion coefficient (ADC) to differentiate between benign and malignant thyroid nodules
In conclusion, diffusion-weighted MRI (DWI) with the ADC values may be feasible, non-invasive and non-radiative method of distinguishing malignant from benign thyroid nodules that do not require the administration of contrast media
Summary
There is a great increase in the incidence of thyroid cancer. Thyroid cancer is the most common endocrine tumor.Thyroid ultrasonography can provide information with regard to nodule diameter, structure of the nodule whether cystic or solid, presence of calcification, regular margin and absence of halo sign but still no reliable criteria for distinguishing benign from malignant lesions. It is difficult to diagnose the malignancy of the nodule when it is large or multinodular[1] Diagnostic imaging examinations such as radionuclide scintigraphy and sonography are commonly used to attempt differentiation between benign and malignant thyroid nodules. These modalities have many limitations, such as poor accuracy with sonography and exposure to ionizing radiation with nuclear scintigraphy[2]. Magnetic resonance imaging (MRI) has gained importance in the diagnosis of thyroid cancer. The application of diffusion-weighted MRI (DWI) is an important diagnostic tool for assessing in vivo tumor characterization. Objective: The purpose of the study is to evaluate the diagnostic accuracy of diffusion weighted imaging and ADC to differentiate between benign and malignant thyroid nodules.
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