Abstract

Dictyostelium development is orchestrated by diffusible signals. Progress has been made in understanding how cAMP signalling triggers post-aggregative development and in defining the number of cell types that eventually differentiate. Ammonia is an unusual signal that may act by alkalinizing acidic vesicles. A chlorinated signal, differentiation-inducing factor (DIF), may be universal amongst the slime moulds. The first genes have been cloned using restriction enzyme mediated integration (REMI) insertional mutagenesis; one encodes a novel cytosolic protein essential for activation of adenylyl cyclase.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.