Abstract

Background: Differentiated thyroid carcinoma (DTC), which includes the papillary and follicular variants, is a common neoplasm. DTC has a very high cure rate and is treated surgically, usually followed by ablation of the post-surgical remnant with radioiodine. Case Presentation: The case of a 68-year-old male patient who underwent a minimally invasive complete thyroidectomy on July 4, 2007 for capsulated follicular carcinoma with margins of excision exempted from neoplastic infiltration (AJCC 2002 pT2 PNX PMX) is presented. Discussion: As the patient showed the presence of a pulmonary metastasis after 11 years, the potential implications of DTC follow-up management are here summarized. Conclusions: Follow up must be continued throughout life.

Highlights

  • Differentiated thyroid carcinoma, which includes the papillary and follicular variants, is a common neoplasm whose incidence has increased in recent years, probably due to heightened medical surveillance and more addressability to surgery

  • In February 2018 the patient underwent a new course of 131I therapy after systems (Tumor, Nodes, Metastases), the AGES (Age, Grade, Extent, Size), the MACIS (Metastases, stimulation with Recombinant human TSH (rh-TSH) (0.9 mg i.m.); on the second day the serum Tg values reached 10.77 ng/mL

  • The postoperative evaluation of the serum Tg test is recommended

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Summary

Introduction

Differentiated thyroid carcinoma, which includes the papillary and follicular variants, is a common neoplasm whose incidence has increased in recent years, probably due to heightened medical surveillance and more addressability to surgery. In this way, many cancers are diagnosed while under one cm [1]. The 10-year overall survival rates for papillary and follicular carcinomas are reported in many cases of 93% and 85%, respectively, with a weak dependence on age or differentiation of the tumor. The risk of persistent or recurrent disease must be reassessed depending on the initial therapy response [12,13,14]

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