Abstract

Nasal mucosal innate host defense is essential for suppressing growth of pathogenic organisms and proper functioning of the upper airways. It has been recognized for long that sinonasal tissues express antimicrobial proteins important in host defense; however the regional distribution of these antimicrobial proteins in upper airways has not been studied in detail. In this study we analyzed the expression of selected antimicrobial proteins in sinonasal tissues at the front (inferior turbinate-IT) and rear (uncinate tissue - UT) of the anterior chamber of the nose in control subjects.

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