Abstract
To identify potential differences in emotional reactivity in high (HAS) and low (LAS) alcohol-sensitive rats in open field tests, 20 ethanol naive, 19th generation HAS and 20 LAS rats from the University of Colorado's Alcohol Research Center each received three consecutive daily 20-min exposures to a 1-sq m open field. The results of repeated-measures ANOVA and Keuls tests, performed on each of five concurrently recorded behaviors, indicated that, compared to HAS rats, LAS animals exhibited significantly greater latencies to begin ambulation, elevated ambulation, and rearing scores that failed to habituate over 3 days, and an increasing intersession bolus count. In addition, significant positive correlations occurred between days 2 + 3 (but not day 1) ambulation and bolus counts in LAS but not HAS rats, and between day 1 ambulation and (i) rearings and (ii) center square entries in HAS but not LAS rats. Together with other cited data, these results provide support for a hypothesis of relatively greater emotional reactivity in LAS rats and illustrate the need for multiple measures and sessions in evaluating open field behavior.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.