Abstract

Mean PCT levels were more elevated in patients with active infection, significantly higher on day 0 and onwards in the 26.5% of fatal cases, compared to that survivors (53.6 vs 27.3; P = 0.01). No clearly defined threshold level indicated an individual occurrence of fatality, however there was a clear different profile of evolution of PCT levels on the 3 days of observation: they significantly decreased by day 1 in surviving patients (P < 0.001), contrary to fatal cases, indicating that PCT level and kinetics could be of use to predict a reduced risk of fatality in patient with cerebral malaria. from Infectious diseases of the nervous system: pathogenesis and worldwide impact Paris, France. 10–13 September 2008

Highlights

  • Differential kinetics of plasma procalcitonin levels in cerebral malaria in urban Senegalese patients according to disease outcome

  • Infectious diseases of the nervous system: pathogenesis and worldwide impact Roberto Bruzzone, Monique Dubois-Dalcq, Georges E Grau, Diane E Griffin and Krister Kristensson Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here.

  • This study analyses the association between serum levels of Procalcitonin (PCT), a marker of septic inflammation, and clinical outcome in 98 Senegalese patients, hospitalised with cerebral malaria

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Summary

Introduction

Infectious diseases of the nervous system: pathogenesis and worldwide impact Roberto Bruzzone, Monique Dubois-Dalcq, Georges E Grau, Diane E Griffin and Krister Kristensson Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here. . Differential kinetics of plasma procalcitonin levels in cerebral malaria in urban Senegalese patients according to disease outcome

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