Abstract
Aim: To explore the underlying genetic reasons of Enterovirus D68 (EV-D68) for its differential epidemiological patterns among continents. Materials & methods: Four hundred and sixty complete VP1 sequences of EV-D68 from GenBank were analyzed with phylodynamics approaches. Results: Sharp bottlenecks of viral population dynamics in 2014 were observed to be strongly correlated with pandemic prevalence of EV-D68; multi-clade distribution of EV-D68 in the USA and Germany in the time-scaled maximum clade credibility tree of total EV-D68 was also a discriminative feature between pandemic and sporadic prevalences. Conclusion: These findings provide insights into the phylogenetic features of EV-D68 correlated with its differential epidemiological patterns among continents.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
