Abstract
The effects on vascular resistance of increasing blood temperature, from hypothermic to hyperthermic levels, were evaluated on denervated perfused spleens and kidneys in the dog. Temperature of the perfusate (blood) was increased for variable intervals of time from the hypothermic level of 32 C to the hyperthermic level of 42 C. The calculated resistance in the splenic vascular bed increased, whereas the resistance decreased in the renal vascular bed. It is concluded that heat has a differential effect in the splenic and renal vascular bed, causing vasoconstriction in the spleen and vasodilation in the kidney.
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