Differential Effects Of Acute And Chronic Exercise On Hdl-cholesterol In Overweight/obese Men And Women

Abstract

PURPOSE: To assess the response of HDL-cholesterol (HDL-C) and its subfractions to acute exercise and to exercise training in previously sedentary overweight/obese men and women. METHODS: Overweight/obese men and women (n = 17, BMI = 31.9 ± 1.3, % body fat = 40.3 ± 1.6) participated in the study. Subjects refrained from non-study exercise and maintained normal dietary habits during the study. Prior to training, subjects were exercised on a motorized treadmill at 70% VO2MAX, 400 kcal energy expenditure during the exercise session. This was followed by a progressive 12-wk exercise training program, including 3 sessions per week, building to 500 kcal per session (1500 kcal per week). Following exercise training, the original acute exercise session was repeated. Blood samples were obtained immediately prior to and 24h after the acute exercise sessions, and analyzed for serum lipids and lipoproteins adjusted for plasma volume shifts. RESULTS: Data were analyzed using a 3 (gender) X 2 (training) X 2 (acute exercise) ANOVA, repeated for training and acute exercise, a was set at < 0.05. Body mass was reduced following training (95.9 kg ± 5.1 to 94.0 kg ± 4.95). Significant HDL-C effects are presented in the table.TableCONCLUSIONS: Exercise appears to have a greater effect on HDL-C and its components in obese men than women. Exercise training at 1500 kcal per week, which induced weight loss, appears to be more potent at producing beneficial changes in HDL-C than acute exercise (400 kcal), regardless of training, in overweight and obese men and women. Supported in part by the Huffines Institute for Sports Medicine and Human Performance