Abstract
AbstractThe effect of an injection of 200 mg/kg para‐chlorophenylalanine (PCPA) on sleep was studied in 6 cats 48—72 h after the injection. Each cat was also given a control injection of the vehicle (BRIJ 35) 3 weeks before or after the experimental dose, in a balanced order. The main effect of PCPA was a reduction of the deep slow wave sleep (DSWS), with little effect upon the light slow wave sleep (LSWS) or rapid eye movement (REM) sleep. Both the number and the length of the DSWS episodes were reduced. For LSWS, only the length of the episodes was reduced. The number and the length of the REM sleep episodes were not changed. When the DSWS was reduced to 10 % or less of control values, there was a tendency to a decrease of LSWS and REM sleep also.
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