Abstract
1. The luteinizing hormone activity in gonadotropin preparations from human and equine pituitaries, human chorionic gonadotropin and pregnant mare serum was inactivated by digestion with alpha-chymotrypsin. By contrast, the luteinizing hormone activity of a human postmenopausal urinary gonadotropin preparation was resistant to enzymic digestion. 2. As with human, ovine and porcine pituitary gonadotropin preparations, human postmenopausal urinary follicle stimulating hormone was not inactivatedinactivated by chymotryptic digestion. This hormonal activity, however, was destroyed by the enzyme in preparations from equine pituitaries and pregnant mare serum. 3. The results suggest that differences exist between pituitary and urinary LH, and between equine FSH and FSH from the other sources studied. These dissimilarities are presumably a reflection of structural differences in the neighborhood of the biologically active site on these hormones. (Endocrinology 84: 9, 1969)
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
