Abstract

MRI plays an essential role in patients before treatment for uterine mesenchymal malignancies. Although MRI includes methods such as diffusion-weighted imaging and dynamic contrast-enhanced MRI, the differentiation between uterine myoma and sarcoma always becomes problematic. The present paper discusses important findings to ensure that sarcomas are not overlooked in magnetic resonance (MR) images, and we describe the update in the differentiation between uterine leiomyoma and sarcoma with recent reports.

Highlights

  • Uterine sarcoma is a malignant tumor of the uterine mesenchymal tumor that occurs in 0.7% of every 100,000 women and accounts for 3–7% of all malignant uterine tumors [1]

  • An magnetic resonance imaging (MRI) scan is useful in differentiating between uterine myoma and sarcoma because a typical

  • In T1-weighted images (T1WI), there are more equivalent signals or relatively low signals compared to those for normal muscle layer, and in T2-weighted images (T2WI), mass is depicted in signals that are patently lower than those for normal muscle layer (Figure 1)

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Summary

Introduction

Uterine sarcoma is a malignant tumor of the uterine mesenchymal tumor that occurs in 0.7% of every 100,000 women and accounts for 3–7% of all malignant uterine tumors [1]. Among all types of uterine sarcomas, leiomyosarcoma (LMS) is highly malignant with an adverse prognosis, and even in. Stage I, its 5-year survival rate is approximately 50%, with this figure reported to decrease less than. 20% from Stage II onward [2]. Diagnosis and treatment of uterine sarcoma involve major problems, and it is well-known that establishing a definitive preoperative diagnosis of uterine sarcoma is difficult. One of the challenges in diagnosing uterine sarcoma is differentiating it from degenerated uterine leiomyoma. Magnetic resonance imaging (MRI) is often used to establish the proper diagnosis, currently, definitive differentiation between uterine sarcoma and degenerated uterine leiomyoma remains difficult. The present paper discusses important findings to ensure that sarcomas are not overlooked in magnetic resonance (MR) images. It should be noted that sarcomas include LMS, low-grade endometrial stromal sarcomas (LGESSs), and high-grade endometrial stromal sarcomas (HGESSs) and exclude carcinosarcomas

MR Imaging Sequences Required for Evaluation
Procedures for the Interpretation of MR images
Modality of Evaluation Images
MR Image Findings
MR Images of Uterine Sarcoma
Leiomyosarcoma
Differentiating between
Update on Differential Diagnosis of Uterine Myoma and Sarcoma
Conclusions

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