DIFFERENTIAL DIAGNOSIS OF JAUNDICE IN THE CLINIC OF INFECTIOUS DISEASES

Abstract

Aims: The purpose of the study is to study the clinical and laboratory features of jaundice with the identification of the most informative differential diagnostic signs of diseases in patients sent to an infectious inpatient facility. Materials and methods. 127 outpatient and inpatient maps of patients with jaundice syndrome were analyzed. Additional methods of investigation (general and biochemical blood tests, serological and genetic-molecular markers of viral hepatitis, FGDS, ultrasound, CT and MRI of abdominal cavity organs) were used. Results. Conducted a comprehensive analysis of the clinical anamnesis data and additional tests patients referred to hospital infectious clinical № 4 Ufa with suspected acute, chronic hepatitis and cirrhosis of viral etiology. The most informative clinical and anamnestic data, clinical-biochemical and seroimmunological indices in the differential diagnosis of superhepatic, hepatic non-viral etiology and subhepatic jaundice caused by acute surgical pathology (toxic hepatitis, Gilbert’s syndrome, calculous cholecystitis, acute pancreatitis) and oncological diseases of the abdominal cavity organs (liver, pancreas, stomach, intestines). As a result, non-infectious jaundice was established and patients were transferred to profile hospitals. The conclusion. Timely correct evaluation of the type of jaundice determines further medical tactics, the volume of medical measures and the place of their conduct. In the differential diagnosis of jaundice should carefully analyze the clinical and medical history, liver function tests, also use additional instrumental examination methods.