Abstract
Chronic recurrent multifocal osteomyelitis (CRMO) is a term, referred to a group of several autoinflammatory disorders (some of unknown genetic background) of children and young adults that is characterized by non-infectious osteomyelitis with or without high inflammatory activity and occasionally involvement of other organs. Patients typically present with bone pain secondary to multifocal osseous lesions, the disease has a remitting course. To specialists who care for patients with autoinflammatory disorders the clinical presentation of CRMO is very recognizable. Yet in the settings of multi-specialty clinic, a newly referred patient with bone lesions poses a certain diagnostic challenge and thorough differential diagnosis is required.
Highlights
Chronic recurrent multifocal osteomyelitis (CRMO) is a term, referred to a group of several autoinflammatory disorders of children and young adults that is characterized by non-infectious osteomyelitis with or without high inflammatory activity and occasionally involvement of other organs
Patients typically present with bone pain secondary to multifocal osseous lesions, the disease has a remitting course
To specialists who care for patients with autoinflammatory disorders the clinical presentation of CRMO is very recognizable
Summary
Introduction Chronic recurrent multifocal osteomyelitis (CRMO) is a term, referred to a group of several autoinflammatory disorders (some of unknown genetic background) of children and young adults that is characterized by non-infectious osteomyelitis with or without high inflammatory activity and occasionally involvement of other organs.
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