Abstract
Our purpose is to summarize the actual knowledge about melanocytic lesions of the ocular surface (conjunctival nevus, primary acquired melanosis and conjunctival melanoma),especially their clinical appearance, differential diagnosis and treatment. Conjunctival nevus is the most common benign, conjunctival melanocytic lesion. Primary acquired melanosis mainly presents in middle-aged or elderly individuals, characterized by proliferation of melanocytes of the conjunctival epithelial layer. Conjunctival melanoma is a rare tumor, it is the second most common malignant ocular surface tumor after ocular surface squamous neoplasia and the third most common ocular malignancy following choroideal malignant melanoma and ocular surface squamous neoplasia. Early recognition and proper management of conjunctival melanoma is indispensable due to its high malignant and metastatic potential. Due to frequent recurrences, the knowledge and use of intra- and postoperative adjuvant treatment modalities, and regular follow-up are necessary. Orv Hetil. 2020; 161(15): 563–574.
Highlights
Differential diagnosis and management of melanocytic lesions of the ocular surface Our purpose is to summarize the actual knowledge about melanocytic lesions of the ocular surface, especially their clinical appearance, differential diagnosis and treatment
Topical interferon alfa in the treatment of conjunctival melanoma and primary acquired melanosis complex
Summary
Célunk a pigmentsejt-eredetű szemfelszíni elváltozások (conjunctivalis naevus, primer szerzett melanosis és conjunctivalis melanoma) összefoglaló ismertetése, különös hangsúlyt fektetve a klinikai megjelenésre, differenciáldiagnosztikára és kezelésre. A primer szerzett (akvirált) melanosis közép- vagy időskorúakban jelenik meg, a conjunctivalis hám melanocytáinak proliferációja következtében. Kulcsszavak: naevus, rasszhoz kötött melanosis, primer szerzett melanosis, conjunctivalis melanoma. Differential diagnosis and management of melanocytic lesions of the ocular surface Our purpose is to summarize the actual knowledge about melanocytic lesions of the ocular surface (conjunctival nevus, primary acquired melanosis and conjunctival melanoma), especially their clinical appearance, differential diagnosis and treatment. Primary acquired melanosis mainly presents in middle-aged or elderly individuals, characterized by proliferation of melanocytes of the conjunctival epithelial layer. Tóth G, Szalai E, Csákány B, Hécz R, Sándor GL, Lukáts O, Nagy ZZs, Szentmáry N.
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