Differential approach to the diagnosis of sleep disorders at Prakinson’s disease

Abstract

To study the differential approach to the diagnosis of sleep disorders in at Prakinson’s disease 30 patients with Parkinson's disease (PD) at the 1st and 2nd stage were studied. The average age of patients were 57 ± 3.5 years, from them 12 women and 18 men. All patients were divided into two comparison groups according to psycho-emotional disorders. For the analysis of sleep disorders conducted polysomnography. The hospital anxiety and depression scale (HADS) was used to identify psycho-emotional disorders. According to the results of HADS, the patients were divided into two comparison groups: the first group included 17 patients with clinically severe depression (average score 15 ± 6.5); the second - 13 patients with clinically severe anxiety (average score 14 ± 4.5) [ρ ≥ 0.05]. The results of polysomnography in both groups showed that in the first group there was a high incidence of increased motor activity during the fast sleep phase (67%), in 5% of cases, sleep apnea was observed. In the second group, a high level of sleep fragmentation was noted (74%), the parasomnia was significantly lower (15%) [ρ ≥ 0.05]. According to the results of the study, it is clear that parasomnia is often accompanied by clinically severe depression, in turn, sleep fragmentation with prolonged daytime sleepiness is observed in severe anxiety, which may be one of the diagnostic criteria for choosing a method for correcting of sleep disorders in Parkinson's disease.