Abstract
Cocaine is a potent psychostimulant whose use gained popularity within the United States in the late 1970′s and extends well into today. The high abuse rate and addictive nature of cocaine has led to an increase in the amount of infants born to cocaine abusing mothers. However, the full extent of its effects on the development of offspring exposed during gestation has yet to be elucidated. The purpose of this experiment is to evaluate maternal weight, litter size, pup weight, and pup brain weight in Sprague‐Dawley rat pups following prenatal cocaine exposure. Maternal and pup total body weight were significantly decreased following prenatal cocaine exposure. However, differences in litter size and pup brain weights were not observed. Data obtained from this study will lay the foundation for determining cocaine's deleterious effects in offspring as well as facilitate cross‐species comparisons of prenatal cocaine exposure.
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