Different treatment modalities in the treatment of childhood lichen planus

Abstract

Introduction: Although rarely described in the Western literature, childhood lichen planus (LP) is noticed much more frequently in the Indian subcontinent. Oral and potent topical corticosteroids commonly used for the treatment of childhood LP can result in significant side effects. Methods: In a open non-randomized follow up study of 49 children, various treatment modalities were tried based on inclusion exclusion criteria. Results: A total of 49 children had generalized or localized LP, of which 5 patients did not complete prescribed therapy. Out of 25 patients who were started with oral dapsone, a total of 20 patients completed therapy. These patients showed a significant improvement showing relief from itching associated with flattening of lesions. Complete response was seen in three-fourth of metronidazole-treated patients by 20 weeks. Remaining 11 patients who were treated oral, topical, or intralesional therapy also showed improvement as predicted. Dapsone and metronidazole therapy did not result in any side effects in this study. Conclusion: Dapsone can be utilized as an effective steroid-sparing agent in the treatment of childhood LP.