Abstract
Multiple myeloma (MM) is a malign hematologic disorder characterized by malign proliferation of plasma cells. Bone marrow examination are necessary for diagnosis, management of disease and prognosis. There are many case of literature related that amounts and morphology of cells in bone marrow biopsy and bone marrow aspiration have an impact on survival, classification and critical management of disease. We presented a rare case of myeloma with plasma cells clustered in the bone marrow aspiration.
Highlights
Multiple myeloma (MM) is a plasma cells dyscrasia
There are multiple myeloma varieties that do not produce monoclonal immunoglobulins, ıt is characterized by a proliferation of monoclonal immunoglobulin producing plasma cells
Disease occurs in many ways such as persistent pain in bone, fewer, fatigue, renal dysfunction, hypercalcemia or rarely with primary systemic amyloidosis
Summary
There are multiple myeloma varieties that do not produce monoclonal immunoglobulins, ıt is characterized by a proliferation of monoclonal immunoglobulin producing plasma cells. It is more frequently seen in men between sixth and seventh decades of life. Disease occurs in many ways such as persistent pain in bone, fewer, fatigue, renal dysfunction, hypercalcemia or rarely with primary systemic amyloidosis. Multiple myleoma is a common cause of amyloidosis In this case, our patient presented specific cardiac amyloidosis and proteinuria depended on renal involvement. The most important step is prove the clonal bone marrow plasma cells ≥10 percent or biopsy-proven bony or soft tissue plasmacytoma [3]. We underline interesting, grouped plasma cells in bone marrow aspiration [Figure 1]
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